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Juha Rouru Selected Research

ORM-12741

12/2020Application of the PET ligand [11C]ORM-13070 to examine receptor occupancy by the α2C-adrenoceptor antagonist ORM-12741: translational validation of target engagement in rat and human brain.
1/2017Tolerability of ORM-12741 and effects on episodic memory in patients with Alzheimer's disease.
5/2014A double-blind, randomized, placebo-controlled crossover trial of the α2C-adrenoceptor antagonist ORM-12741 for prevention of cold-induced vasospasm in patients with systemic sclerosis.

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Juha Rouru Research Topics

Disease

1Brain Diseases (Brain Disorder)
12/2020
1Alzheimer Disease (Alzheimer's Disease)
01/2017
1Hypoglycemia (Reactive Hypoglycemia)
03/2015
1Systemic Scleroderma (Systemic Sclerosis)
05/2014
1Anxiety Disorders (Anxiety Disorder)
12/2005

Drug/Important Bio-Agent (IBA)

3ORM-12741IBA
12/2020 - 05/2014
1G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA
12/2020
1Atomoxetine Hydrochloride (Strattera)FDA LinkGeneric
03/2015
1Insulin (Novolin)FDA Link
03/2015
1KetamineFDA LinkGeneric
03/2015
1Norepinephrine (Noradrenaline)FDA LinkGeneric
03/2015
1deramciclaneIBA
12/2005